Endocrine Abstracts

The healing effects of Hevea brasiliensis latex biomembrane has been widely cited in the literature, mainly regarding its protein fraction F1 in patients with diabetes. The purpose of this study was to evaluate the wound healing mechanism of F1 in diabetic rats. Eighty Wistar rats were used for the experiments, where: 40 rats were induced to diabetes by streptozotocin 45 mg/kg (DM) and 40 rats were left non-diabetic (N). Two wounds were created on the dorsal of each rat using ...

Background: Several studies on diabetes mellitus and cutaneous wounds have been reported. However, only few studies show the influence of diabetes on the skin regarding its oxidative stress, antioxidants mechanisms and histopathological aspects.Objectives: The aim of this study was to evaluate these parameters by comparing them to non-diabetic rats skin.Methods: Ten Wistar rats were assigned to groups: diabetic rats (induced by str...